Alternatives for treating antibiotic-resistant pathogens

Alternative therapeutic strategies to treat antibiotic-resistant pathogens

  • Craig R. MacNair
  • Steven T. Rutherford
  • Man-Wah Tan
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    The Accelerator will identify microbiome research with the potential to transform human health outcomes. Four carefully chosen applicants will be awarded $10,000 and gain entry to our immersive residential programme that provides the training/mentorship, and connections to translate groundbreaking research for maximum impact. Deadline for applications is 24 June 2024.

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  • This study shows that a single-stranded RNA phage binds to the Pseudomonas aeruginosa type IV pilus, leading to phage entry into the cell and the detachment of the pilus, which impairs bacterial motility.

    • Andrea Du Toit
    Research Highlight
  • In this study, Granton et al. show that biofilm-associated exopolysaccharides produced by Pseudomonas aeruginosa control sickness during lung infection.

    • Agustina Taglialegna
    Research Highlight
  • This Genome Watch article highlights the recent use of large-scale monitoring of natural microbiomes to examine feedback between environmental change and microbial adaptation.

    • Sharon Greenblum
    Genome Watch
  • In this study, Armani-Tourret et al. show that the combination of panobinostat and pegylated interferon-α2a transforms the structure and composition of the HIV-1 reservoir and could potentially counter it.

    • Agustina Taglialegna
    Research Highlight
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The COVID-19 pandemic, caused by the coronavirus SARS-CoV-2, has led to substantial disease and millions of deaths worldwide, with devastating socio-economic impacts. This Series contains articles from Nature Reviews Microbiology that explore the basic biology, epidemiology, emergence, evolution and pathogenesis of SARS-CoV-2 and pathogenic coronaviruses, as well as options for the control and prevention of COVID-19.
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