您当前的位置: 首页 > 资源详情

Medicalxpress,11月22日,Pfizer says COVID shot 100% effective in adolescents after 4 months

编译者:YUTING发布时间:Nov 27, 2021点击量:285 来源栏目:最新研究

Pfizer and BioNTech said Monday their COVID-19 vaccine remained 100 percent effective in children 12 to 15 years old, four months after the second dose.

The companies said that the new data, which involved 2,228 trial participants, will help support their applications for full approval in the United States and worldwide.

No serious safety concerns were observed in individuals with at least six months of follow-up after the second dose.

"As the global health community works to increase the number of vaccinated people around the world, these additional data provide further confidence in our vaccine's safety and effectiveness profile in adolescents," said Pfizer CEO Albert Bourla in a statement.

"This is especially important as we see rates of COVID-19 climbing in this age group in some regions, while vaccine uptake has slowed. We look forward to sharing these data with the FDA and other regulators."

The vaccine was granted "emergency use authorization" for adolescents by the US in May and the companies plan to soon seek full approval. The vaccine is currently only fully approved in people aged 16 and older.

Among the 2,228 participants, there were 30 confirmed symptomatic COVID cases without evidence of prior infection, all in the placebo group.

This corresponds to a vaccine efficacy of 100 percent. Efficacy was consistently high across gender, race, obesity levels and comorbidity status.

The main safety concern among this age group is vaccine-linked myocarditis (heart inflammation) in males.

But such cases are very rare, and the benefits of vaccination continue to strongly outweigh the risks, data has shown. COVID itself can cause myocarditis, both more often and a more severe form.

提供服务:导出本资源
  1. 1 Nature,11月10日,Initial whole-genome sequencing and analysis of the host genetic contribution to COVID-19 severity and susceptibility
  2. 2 11月10日_研究人员分析宿主基因对COVID-19严重程度和易感性的影响
  3. 3 11月11日_新冠药物Remestemcel-L二期临床的中期分析结果积极
  4. 4 11月11日_CDC呼吁制定通用口罩规定以减少新冠传播
  5. 5 SSRN,2月20日,Dynamics of the Latest 2019 Novel Coronavirus Disease Epidemic in China: A Descriptive Study
  6. 6 SSRN,2月20日,Mental Health Problems and Social Media Exposure During COVID-19 Outbreak
  7. 7 SSRN,2月20日,Evaluating Incidence and Impact Estimates of the Coronavirus Outbreak from Official and Non-Official Chinese Data Sources
  8. 8 SSRN,2月20日,Clinical Characteristics and Treatment of Patients Infected with COVID-19 in Shishou, China
  9. 9 Nature,11月10日,Mobility network models of COVID-19 explain inequities and inform reopening
  10. 10 1月27日_Nature报道中国新型冠状病毒最新研究进展:病毒传播速度有多快?
  1. 1 Medicalxpress,1月10日,Even symptom-free, people with Omicron are much more likely to spread COVID, say studies
  2. 2 Medicalxpress,1月10日,Researchers use artificial intelligence to guide the search for the next SARS-like virus
  3. 3 1月6日_COVID-19患者味觉改变可能是鼻后嗅觉功能受损的间接结果
  4. 4 Medicalxpress,1月7日,Omicron resistant to most monoclonal antibodies but neutralized by a booster dose
  5. 5 Science,1月6日,Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry
  6. 6 Biospace,1月5日,Clover Doses First Participants with Homologous Booster Dose of COVID-19 Vaccine Candidate in SPECTRA
  7. 7 Medicalxpress,1月4日,Early data for multivariant COVID-19 vaccine booster shows promise
  8. 8 Cell,1月3日,SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses
  9. 9 Medicalxpress,12月30日,Research team discovers a novel vaccine strategy to prevent SARS-CoV-2 nasal infection
  10. 10 Cell,12月27日,Complement activation induces excessive T cell cytotoxicity in severe COVID-19

版权所有@2017中国科学院文献情报中心

制作维护:中国科学院文献情报中心信息系统部地址:北京中关村北四环西路33号邮政编号:100190