Latest Research . Physical sciences . See All Article20 April 2020Open Access High throughput pMHC-I tetramer library production using chaperone-mediated peptide exchange .Peptide-MHC (pMHC) tetramers are important tools for probing T cell repertoire and adaptive immune responses. Here the authors use a molecular chaperone, TAPBPR, to develop a high-throughput, multiplexible platform for pMHC tetramer generation to facilitate simultaneous assessments of T...