Introduction . Positron emission tomography (PET) with ligands against prostate specific membrane antigen (PSMA) seems as an effective noninvasive method for prostate cancer (pCa) characterization and localization1 , 2. Expression of PSMA, addressed by PSMA PET, increases on tumors with higher Gleason score (GS)3 , 4. The most aggressive part of the prostatic tumor, knowing as dominant tumor (DT), usually based on histology, can be assessed by PET, although with a sca...