SERS allows direct optical reading of single-molecule DNA bases . 22?May?2018 Imec's surface-enhanced Raman spectroscopy process could also be used in chemical and biological sensing. Plasmonic nanoslit: single-molecule sensitivity One promising approach to DNA sequencing involves the use of nanopores, exploiting the interactions that can take place between molecules that are mechanically confined within the pore and an ionic current passing through it. Under the ri...