Main . Avidity sequencing chemistry enables a diversity of applications that include single-cell RNA sequencing (RNA-seq) and whole-human-genome sequencing. For the human sample HG002, avidity sequencing reached a single-nucleotide polymorphism (SNP) F1 score of 0.9958 and small-indel F1 score of 0.9954. Over the past 15?years, highly parallel sequencing methods have enabled a broad set of applications1 , 2 , 3 , 4 , 5 , 6 , 7 , 8. Multiple technologies have been ...