General Statements We are pleased to enclose our revised manuscript entitled “Sperm induction of somatic cell-cell fusion as a novel functional test” for a research article. In this work, we present evidence for a new phenomenon, named SPICER, of sperm-induced fusion of cells expressing the oocyte protein JUNO. We showed that this effect depends on JUNO, the sperm fertilizing ability, and the action of the sperm protein IZUMO1. We were glad to receive positive feedback from the reviewers...