TOPLINE: . Hybrid closed-loop (HCL) systems may ease severe diabetes distress in some adults with type 1 diabetes (T1D), but not in adolescents. METHODOLOGY: . Previous findings suggest a 20%-30% prevalence of severe diabetes distress in patients with T1D, which affects self-care, diabetes management, glycemic control, and quality of life (QoL). . IMPLIQUE, a quality-of-life study, assessed the HCL system in 250 adults (mean age, 42.4 years; 58.4% women) and adolescents (m...